The recruitment status of study NCT04348591 (Identifying the Optimal Neural Target for Misophonia Interventions) was changed from “Not yet recruiting” to “Recruiting” on October 30, 2020.
The clinical trial is a collaboration between Duke University and the Misophonia Research Fund. It was first posted six months ago in April 2020.
The goal is to identify neurostimulation targets that could potentially be used in the treatment of misophonia.
Participants will receive real or sham neurostimulation over the prefrontal cortex and insula in a random order, while engaging in listening to versus downregulating misophonic, aversive, or neutral cues. The investigators plan to assess emotional dysregulation, psychopathology, and misophonia with a multi-method battery of measures during all three study appointments. Feasibility and acceptability will be examined qualitatively. The investigators will use results from this study to design larger trials and to seek federal funding with the ultimate goal of designing an effective misophonia intervention. If successful, our study can be the first step in a series of investigations that establish the unique targets for neural intervention for misophonia.
Here is a link to the official study record: